| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10803900 | Biochimie | 2013 | 13 Pages |
Abstract
⺠Apigenin binds purified tubulin and inhibits it polymerization. ⺠Apigenin disrupts microtubule structure and induces apoptosis in A549 cells. âºÂ Apigenin shows synergistic anticancer activity with curcumin. ⺠Apigenin and curcumin synergistically disrupt microtubule network and induce apoptosis. ⺠Apigenin and curcumin bind tubulin simultaneously at two different sites.
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Authors
Diptiman Choudhury, Arnab Ganguli, Debabrata Ghosh Dastidar, Bipul R. Acharya, Amlan Das, Gopal Chakrabarti,