Peptidylarginine deiminase expression and activity in PAD2 knock-out and PAD4-low mice

Article ID	Journal	Published Year	Pages	File Type
10803927	Biochimie	2013	10 Pages	PDF

Abstract

âº The PAD2 and PAD4 proteins are differentially expressed in mouse tissues. âº Disruption of the PAD2 gene eliminates PAD activity in many tissues. âº PAD6 protein expression is enhanced in PAD2 knock-out and PAD4-low mice.

Keywords

PBMC RBC ABAP PMN Citrullination Peptidylarginine deiminase Rheumatoid arthritis Tissue-specific expression neutrophil extracellular trap NET Peripheral blood mononuclear cell polymorphonuclear leukocytes Knock-out mice PAD red blood cell

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

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Peptidylarginine deiminase expression and activity in PAD2 knock-out and PAD4-low mice

Authors

Joyce J.B.C. van Beers, Albert J.W. Zendman, Reinout Raijmakers, Judith Stammen-Vogelzangs, Ger J.M. Pruijn,