| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10803954 | Biochimie | 2012 | 13 Pages |
Abstract
⺠MdtM is a multidrug efflux protein that functions in intrinsic resistance of Escherichiacoli. ⺠MdtM was purified to homogeneity in active form. ⺠MdtM is monomeric and stable in dodecylmaltoside detergent solution. ⺠Purified MdtM binds antibiotic chloramphenicol with nanomolar affinity.
Keywords
decylmaltosideMDRTMSDDMRNDBCASE-HPLCMFSCCCPPMSFSMREtBrBSAbovine serum albuminethidium bromideoctylglucosidetransmembrane segmentMajor facilitator superfamilybicinchoninic acidMultidrug effluxMatePhenylmethanesulfonyl fluorideAntibiotic resistanceMultidrug resistancesmall multidrug resistanceresistance-nodulation-divisionMultidrug And Toxic compound ExtrusionIntegral membrane proteinCarbonyl cyanide 3-chlorophenylhydrazone
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Scarlett R. Holdsworth, Christopher J. Law,