Article ID Journal Published Year Pages File Type
10803956 Biochimie 2012 12 Pages PDF
Abstract
► Nephroprotective role of CI protein in Dox-induced renal damage was investigated. ► Doxorubicine activates both intrinsic and extrinsic apoptotic pathways. ► Doxorubicine activates the MAPKs family proteins. ► CI protein reduced oxidative stress, renal dysfunction and apoptotic cell death. ► CI protein might act as a beneficial agent in Dox-induced renal dysfunctions.
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