Article ID Journal Published Year Pages File Type
10803960 Biochimie 2012 8 Pages PDF
Abstract
► A Sp1/NRF-1 binding site was involved in the IRF-3 minimal promoter activation. ► Sp1 and Sp3, but not NRF-1, positively regulate IRF-3 transcription activity. ► Sp1 and Sp3 increased expression of the IRF-3 gene at the level of transcription.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Transcription factors Sp1 and Sp3 regulate basal transcription of the human IRF-3 gene
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