| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10803986 | Biochimie | 2013 | 9 Pages |
Abstract
⺠We model the cholesterol biosynthesis pathway and its regulation. ⺠The innate immune response leads to a suppression of flux through the pathway. ⺠Statin inhibitors show a different mode of suppression to the immune response. ⺠Statin inhibitor suppression is less robust and less specific than immune suppression.
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Authors
Steven Watterson, Maria Luisa Guerriero, Mathieu Blanc, Alexander Mazein, Laurence Loewe, Kevin A. Robertson, Holly Gibbs, Guanghou Shui, Markus R. Wenk, Jane Hillston, Peter Ghazal,