Article ID Journal Published Year Pages File Type
10803992 Biochimie 2012 10 Pages PDF
Abstract
► DNA methylation occurs on cytosines and is essential for mammalian development. ► DNA methylation undergoes extensive reprogramming during embryogenesis. ► DNA methylation is regulated by DNA binding factors, chromatin and non-coding RNAs. ► 5-Hydroxymethylcytosine might be an intermediate of demethylation.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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Mechanisms of DNA methylation and demethylation in mammals
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