| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10804017 | Biochimie | 2012 | 4 Pages |
Abstract
⺠Identification of natural product NAE inhibitor (1) by virtual screening. ⺠Compound 1 may be a structural mimic NAE inhibitor to ATP and MLN4924. ⺠Compound 1 inhibits NAE activity in both cell-free and cell-based assays. ⺠Compound 1 is selective over analogus E1 enzymes UAE and SAE.
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Authors
Hai-Jing Zhong, Victor Pui-Yan Ma, Zhen Cheng, Daniel Shiu-Hin Chan, Hong-Zhang He, Ka-Ho Leung, Dik-Lung Ma, Chung-Hang Leung,