Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10804066 | Biochimie | 2012 | 4 Pages |
Abstract
⺠P185HER2 distribution in cancer cells was studied electron microscopically. ⺠A novel immunodetection system was used, based on the interaction of barnase with its inhibitor barstar. ⺠4D5 scFv fused with two molecules of barnase and barstar-Au was used as labeling complex. ⺠At 4 °C P185HER2 occurs on the cell surface, at 37 °C its internalization was observed.
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Authors
Julia L. Ivanova, Evelina F. Edelweiss, Olga G. Leonova, Taras G. Balandin, Vladimir I. Popenko, Sergey M. Deyev,