| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10804078 | Biochimie | 2012 | 14 Pages |
Abstract
⺠We purified two serine proteases (BpirSP27/SP41) from Bothrops pirajai snake venom. ⺠Enzymes showed major differences in their sequences, masses and N-glycosylation levels. ⺠BpirSP27 acted on the Bβ chain and BpirSP41 on both Aα/Bβ chains of fibrinogen. ⺠BpirSP41 presented higher coagulant and fibrinolytic potential than BpirSP27. ⺠BpirSP27 induced aggregation of washed platelets to a greater extent than BpirSP41.
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Authors
Danilo Luccas Menaldo, Carolina Petri Bernardes, Norival Alves Santos-Filho, Laura de Andrade Moura, André Lopes Fuly, Eliane Candiani Arantes, Suely Vilela Sampaio,