Article ID Journal Published Year Pages File Type
10804090 Biochimie 2012 9 Pages PDF
Abstract
► CLUSTER analysis was performed on H3Ac/H3K4me/H3K9me ChIP-chip data. ► It shows mRNA expression directly correlates with H3Ac/H3K4me levels. ► H3K9me levels show inverse correlation under hyperglycemia/hyperinsulinemia. ► Increased promoter occupancy of H3Ac/H3K4me and decreased H3K9me on active genes. ► Presence of crosstalk between H3Ac and H3K4me under these conditions.
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