Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10804095 | Biochimie | 2012 | 7 Pages |
Abstract
⺠We examine epigenetic changes in Grb10 in serially passaged adult mouse fibroblasts. ⺠The amount of methylated histone H3K27me3 reduced after extended cultivation. ⺠The amount of acetylated histones H3Ac and H4Ac increased after extended cultivation. ⺠There was a global reduction in DNA methylation after extended cultivation.
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Authors
Jianfeng Yao, Yanfang Huang, Rongfu Huang, Runhai Shi, Peng Chen, Baoqin Zhu, Ming Li, Xiaohong Jiang, Ming Zheng, Yiping Jiang, Xiaoyu Yang,