| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10804114 | Biochimie | 2012 | 7 Pages |
Abstract
⺠Interplay of SR and MD elucidate hydration and packing in model lipid membranes. ⺠Nanosecond SR kinetics of Laurdan displays mobility of acyl groups. ⺠Headgroup packing of PC/TAP revealed by relaxation time and area per lipid reflects nonideal mixing. ⺠Oxidized lipids increase hydration and mobility at the lipid carbonyl level. ⺠Large soft polarizable anions associate with and destabilize lipid bilayers.
Keywords
dMPCPGPCTDFsPOVPCDOTAPOxPLDOPCPoPCLaurdanFCS1,2-dimyristoyl-sn-glycero-3-phosphocholine1,2-dioleoyl-sn-glycero-3-phosphocholine1,2-dioleoyl-3-trimethylammonium-propaneSolvent relaxationlarge unilamellar vesicleMolecular dynamicsfluorescence correlation spectroscopyoxidized phospholipidsPolarizabilityLUVOxidized lipidHofmeisterPatmanPRODAN
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Authors
P. Jurkiewicz, L. Cwiklik, P. Jungwirth, M. Hof,