| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10804115 | Biochimie | 2012 | 9 Pages |
Abstract
⺠Lipophosphoramidate amphiphiles constitute a family of synthetic vectors efficient for in vitro and in vivo gene delivery. ⺠Structural changes modify the physicochemical properties and transfection efficacies. ⺠The use of a trimethylarsonium group as cationic part usually decreases the toxicity and enhances transfection activities. ⺠Imidazole-based neutral lipophosphoramidates are used as helper lipid to enhance transfection activity.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Mathieu Berchel, Tony Le Gall, Hélène Couthon-Gourvès, Jean-Pierre Haelters, Tristan Montier, Patrick Midoux, Pierre Lehn, Paul-Alain Jaffrès,