Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10804116 | Biochimie | 2012 | 17 Pages |
Abstract
⺠The recent research activities using functional lipids for gene delivery are reviewed. ⺠The barriers to efficient gene delivery are described. ⺠The pathways and mechanism(s) of lipoplex uptake in cells are reported. ⺠Functional lipids deliver DNA more efficiently than analogs that do not. ⺠Functional lipids show significant promise for in vitro and in vivo gene transfection.
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Authors
Xiao-Xiang Zhang, Thomas J. McIntosh, Mark W. Grinstaff,