| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10804129 | Biochimie | 2012 | 11 Pages |
Abstract
⺠The PNP is a target for the development of drugs against bacterial diseases. ⺠The structure of MtPNP associated with acyclovir was solved at 2.10 Ã
resolution. ⺠MD simulations were carried out in order to dissect MtPNP:ACY structural features. ⺠The results suggest a possible different role of Phe153 if compared with Phe159.
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Authors
Rafael A. Caceres, LuÃs F.S.M. Timmers, Rodrigo G. Ducati, Diego O.N. da Silva, Luiz A. Basso, Walter F. Jr., Diógenes S. Santos,