| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10804157 | Biochimie | 2012 | 9 Pages |
Abstract
⺠Fluorescent G6Pase is found in perinuclear membranes and in cytoplasmic vesicles. ⺠Despite a high degree of colocation, FRET between both subunits is not detected. ⺠GSD-1 mutations affect neither G6PC nor G6PT localisation. ⺠G6PT adopts a wrapped conformation which is not affected by GSD-1b mutations.
Keywords
G6PTG6PCFPG6PCYFPG6PaseFLIMFluorescence resonance energy transferFRETFluorescence energy transferGlycogen storage diseasefluorescence lifetime imagingendoplasmic reticuluminorganic phosphateGlycogen storage disease type 1yellow fluorescent proteincyan fluorescent proteinglucose-6 phosphateglucose-6 phosphataseglucose-6-phosphate transporterglucose-6-phosphatase
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Authors
Maud Soty, Julien Chilloux, Sylvie Casteras, Alexeï Grichine, Gilles Mithieux, Amandine Gautier-Stein,