| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10804177 | Biochimie | 2012 | 6 Pages |
Abstract
⺠Angeli's Salt (AS) releases nitroxyl (HNO), which acutely activates GLUT1. ⺠A maximum 7-fold activation occurs at 5 mM AS within 2-3 min ⺠HNO stimulation can be blocked by a pretreatment with thiol-reactive compounds. ⺠HNO likely stimulates a disulfide bond within GLUT1, which activates the transporter.
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Authors
Matthew J. Salie, Daniel S. Oram, David P. Kuipers, Jared P. Scripture, Jude Chenge, Griffin J. MacDonald, Larry L. Louters,