| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10804209 | Biochimie | 2011 | 11 Pages |
Abstract
⺠BChE reacts with ethopropazine enantiomers stereoselectively (specific inhibitor of BChE). ⺠Complex mechanism of BChE interaction with the ethopropazine was described. ⺠Inhibition of BChE by racemate can be described using kinetic constants derived for enantiomers. ⺠Three kinetic models for cholinesterases were compared in explaining inhibition mechanism. ⺠Various BChE showed similarity in stereoselectivity while AChE showed a lack of stereoselectivity.
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Authors
Goran Å inko, Zrinka Kovarik, Elsa Reiner, Vera Simeon-Rudolf, Jure Stojan,