| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10804214 | Biochimie | 2011 | 4 Pages |
Abstract
⺠First inhibitor profiling of the metalloprotease ZapA from Proteus mirabilis. ⺠Details important information regarding S1Ⲡand S2Ⲡbinding preferences of ZapA. ⺠Inhibitors have been demonstrated to protect substrates from ZapA-mediated degradation. ⺠May ultimately contribute to elucidation of the role of ZapA during infection. ⺠May lead to development of an 'anti-virulence' approach to management of P. mirabilis infections.
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Authors
Louise Carson, George R. Cathcart, Christopher J. Scott, Morley D. Hollenberg, Brian Walker, Howard Ceri, Brendan F. Gilmore,