| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10804245 | Biochimie | 2011 | 13 Pages |
Abstract
⺠Aggregation is the most riveting topic as most of the diseases are concerned with this phenomenon. ⺠In DM-2 a structural transition from physiological IAPP to pathological deposits takes place. ⺠IAPP aggregation (amyloidosis) takes place due to different acquired or inherited factors. ⺠This is compilation of multidisciplinary approaches to translate into new research opportunities. ⺠It will abet the communication between biologists and chemists to develop agents against amyloids.
Keywords
AFMCGRPCFTRhIAPPNIDDMROSπ–π stackingAmyloidogenesisAmylinIDEtype-2 diabetes mellitusNon-insulin dependent diabetes mellituscystic fibrosis transmembrane conductance regulatorrIAPPendoplasmic reticulumatomic force microscopyhuman islet amyloid polypeptidecalcitonin gene related peptideReactive oxygen species
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Authors
Ejaz Ahmad, Aqeel Ahmad, Saurabh Singh, Md Arshad, Abdul Hameed Khan, Rizwan Hasan Khan,