Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10814899 | Cellular Signalling | 2014 | 13 Pages |
Abstract
Taken together, our observations define a novel mechanism for intrinsically kinase-deficient RTK downregulation and support an intriguing model, where Hsp90 dissociation acts as a trigger for ligand-induced receptor removal.
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Authors
Odette Allonby, Amr M. El Zawily, Tanya Freywald, Darrell D. Mousseau, Jennifer Chlan, Deborah Anderson, Alexandre Benmerah, Vishaldeep Sidhu, Mohan Babu, John DeCoteau, Andrew Freywald,