Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10815323 | Cellular Signalling | 2013 | 11 Pages |
Abstract
⺠Elevated Rho kinase function inhibits autophagy. ⺠Inhibition of Rho kinase enhances starvation-induced autophagic degradative flux. ⺠Enlarged autophagosomal compartments are formed when Rho kinase is inhibited. ⺠Enlarged autophagosomes are enriched for the autophagy regulatory kinase ULK1.
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Authors
Andrzej Mleczak, Sarah Millar, Sharon A. Tooze, Michael F. Olson, Edmond Y.W. Chan,