| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10815331 | Cellular Signalling | 2013 | 11 Pages |
Abstract
⺠PHD finger protein 20 (PHF20) is a firstly identified in glioma patients. ⺠PKB can directly phosphorylate PHF20 on Ser291 in vitro and in vivo. ⺠PHF20 phosphorylation by PKB led to an inhibition of UV-mediated p53 induction. ⺠Expression of PHF20 and PKB activity is correlated in various human cancer tissues. ⺠PHF20 is a novel substrate for PKB and could be a key target for glioma patients.
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Authors
Yuwen Li, Jisoo Park, Longzhen Piao, Gyeyeong Kong, Yongbaek Kim, Kyeong Ah Park, Tiejun Zhang, Janghee Hong, Gang Min Hur, Jeong Ho Seok, Seung-Won Choi, Byong Chul Yoo, Brian A. Hemmings, Derek P. Brazil, Seon-Hwan Kim, Jongsun Park,