Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10815351 | Cellular Signalling | 2013 | 13 Pages |
Abstract
⺠Dvl-2 and Dvl-3 (Dvls) are highly expressed in ALK+ALCL, a type of T-cell lymphoma. ⺠Dvls contribute to cell growth and tumorigenicity of ALK+ALCL. ⺠Dvls transduce signals via the Wnt non canonical pathways, namely via NFAT and Src. ⺠Dvl proteins are novel NPM-ALK interacting proteins and possibly NPM-ALK substrates.
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Authors
Samar A. Hegazy, Abdulraheem Alshareef, Pascal Gelebart, Mona Anand, Hanan Armanious, Robert J. Ingham, Raymond Lai,