Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10815353 | Cellular Signalling | 2013 | 13 Pages |
Abstract
⺠βarrestin2 interacts with TβRII in the absence of TβRIII. ⺠βarrestin2 traffics with TβRII and enhances the interaction of TβRII with SARA. ⺠βarrestin2 siRNA increases cell surface TβRII levels, Smad2 and p38 phosphorylation. ⺠βarrestin2 siRNA-dependent phosphorylation of p38 correlates with increased apoptosis.
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Authors
Sarah McLean, Moshmi Bhattacharya, Gianni M. Di Guglielmo,