Article ID Journal Published Year Pages File Type
10815353 Cellular Signalling 2013 13 Pages PDF
Abstract
► βarrestin2 interacts with TβRII in the absence of TβRIII. ► βarrestin2 traffics with TβRII and enhances the interaction of TβRII with SARA. ► βarrestin2 siRNA increases cell surface TβRII levels, Smad2 and p38 phosphorylation. ► βarrestin2 siRNA-dependent phosphorylation of p38 correlates with increased apoptosis.
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