Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10815400 | Cellular Signalling | 2012 | 12 Pages |
Abstract
⺠EGF and VIP specifically control spatiotemporal ERK dynamic. ⺠Ras is specifically required for EGF-activated ERK nuclear pool. ⺠Ras is required for both cytoplasmic and nuclear pools of VIP-activated ERK. ⺠Rap1 is exclusively involved in VIP-activated ERK nuclear pool. ⺠Ras and Rap1 are differentially involved in ERK nuclear translocation.
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Authors
Caroline Zeiller, Marie-Pierre Blanchard, Morgane Pertuit, Sylvie Thirion, Alain Enjalbert, Anne Barlier, Corinne Gerard,