| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10815536 | Cellular Signalling | 2012 | 6 Pages |
Abstract
⺠C2GNT activation is dependent on the production of ROS by NADPH oxidase. ⺠Lack of NADPH oxidase results in decreased leukostasis. ⺠Novel signaling pathway between TNF-α, NADPH oxidase, PKCβ1/2 and C2GNT identified.
Keywords
PKCC2GnTBRECSLexCD62PL-selectinCD62LP-selectinE-selectinPMNICAM-1GlcNAcNADPHROSinflammationNADPH oxidasetumor necrosis factor-alphadiabetic retinopathyVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)TNF-αLeukostasisintracellular adhesion molecule-1nicotinamide adenine dinucleotide phosphateProtein kinase CPolymorphonuclearAdhesionReactive oxygen species
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Authors
Joanna M. Tarr, Ning Ding, Kirti Kaul, Anna Antonell, Luis A. Pérez-Jurado, Rakesh Chibber,