Article ID Journal Published Year Pages File Type
10815549 Cellular Signalling 2012 8 Pages PDF
Abstract
► BMP signaling inhibition by Dorsomorphin (DM) abrogates mitotic arrest. ► TGF-β signaling inhibition by SB431542 does not abrogate mitotic arrest. ► DM, noggin and SMAD1, 5, 4 knockdown downregulate checkpoint proteins. ► BMP and Activin signaling regulate mitotic checkpoint protein levels differentially. ► Overexpressing some mitotic genes significantly rescues mitotic defect caused by DM.
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