Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10815549 | Cellular Signalling | 2012 | 8 Pages |
Abstract
⺠BMP signaling inhibition by Dorsomorphin (DM) abrogates mitotic arrest. ⺠TGF-β signaling inhibition by SB431542 does not abrogate mitotic arrest. ⺠DM, noggin and SMAD1, 5, 4 knockdown downregulate checkpoint proteins. ⺠BMP and Activin signaling regulate mitotic checkpoint protein levels differentially. ⺠Overexpressing some mitotic genes significantly rescues mitotic defect caused by DM.
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Authors
Hualong Yan, Songcheng Zhu, Chenlin Song, Naifa Liu, Jiuhong Kang,