Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10815553 | Cellular Signalling | 2012 | 7 Pages |
Abstract
⺠The IGF system is involved in the development of diverse types of cancer. ⺠Estrogens play a main role in the progression of breast and endometrial tumors. ⺠ERα, ERβ and GPER mediate the estrogen signaling. ⺠A cross talk between IGF-I and estrogens contribute to cancer progression. ⺠Co-targeting estrogen and IGF-I signaling may improve anticancer strategies.
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Authors
Viviana Bartella, Paola De Marco, Roberta Malaguarnera, Antonino Belfiore, Marcello Maggiolini,