| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10815589 | Cellular Signalling | 2012 | 13 Pages |
Abstract
⺠TPX2 acts as a co-activator protein for Aurora B kinase. ⺠TPX2 serves as a scaffold protein for assembly of the Chromosomal Passenger Complex. ⺠Overexpression of TPX2 B causes mitotic defects that reflect Aurora B inhibition. ⺠The levels of TPX2 correlate with Aurora B activity in pancreatic cancer cells.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Jyoti Iyer, Ming-Ying Tsai,