Article ID Journal Published Year Pages File Type
10815595 Cellular Signalling 2012 9 Pages PDF
Abstract
► Down-regulation of PDCD5 was identified in osteosarcoma cell line, MG-63. ► PDCD5 induced apoptosis, G2 arrest, and inhibited cell proliferation in MG-63. ► PDCD5 suppressed MG-63 via the Ras/Raf/MEK/ERK signaling pathway. ► The N (3-40) and C (102-125) terminal residues of PDCD5 did not exhibit activity.
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