Article ID Journal Published Year Pages File Type
10815678 Cellular Signalling 2012 8 Pages PDF
Abstract
► Binding of transferrin to the receptor induces generation of cell surface ceramide. ► Down regulation of acid sphingomyelinase disturbs transferrin uptake and recycling. ► Lack of ceramide facilitates translocation of transferrin receptor to rafts. ► Ceramide favors uptake of transferrin receptor by clathrin-depended pathway.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
, , , ,