| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10815696 | Cellular Signalling | 2012 | 9 Pages |
Abstract
⺠Endogenous α1-ARs localize to the nucleus in adult cardiac myocytes. ⺠Nuclear localization sequences drive α1-ARs to the nuclei in adult cardiac myocytes. ⺠α1-AR signaling is initiated in the nucleus in adult cardiac myocytes. ⺠α1-ARs form oligomers that alter receptor function in adult cardiac myocytes.
Keywords
NCXp-ERKβgalAlpha1-adrenergic receptorNa+/Ca2 + exchangerGAPDHLAP2ERKOligomerα1-ARGPCRβ-ARG-protein coupled receptorMOIFörster resonance energy transferFRETbeta-galactosidaseBODIPYendoplasmic reticulumphenylephrineLeptomycin BCardiac myocytewild-typemultiplicity of infectionextracellular-regulated kinaseglyceraldehyde 3-phosphate dehydrogenaseα1-Adrenergic receptorβ-Adrenergic receptorG protein-coupled receptor
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Authors
Casey D. Wright, Steven C. Wu, Erika F. Dahl, Alan J. Sazama, Timothy D. O'Connell,