Leucine induced dephosphorylation of Sestrin2 promotes mTORC1 activation

Article ID	Journal	Published Year	Pages	File Type
10815868	Cellular Signalling	2016	47 Pages	PDF

Keywords

mTORC1 Atg13 p70S6K1 Rag GTPases 70 kDa ribosomal protein S6 kinase 1 RHEB LARS FIP200 RAG ULK1 4E-BP1 eukaryotic initiation factor 4E binding protein 1 PP2A AMPK MEF mTOR V-ATPase TSC SLC AMP-activated protein kinase Vacuolar ATPase mTOR complex 1 Amino acids solute carrier Ras homolog enriched in brain leucyl-tRNA synthetase Signaling GAP mouse embryo fibroblasts Mechanistic target of rapamycin protein phosphatase 2A Tuberous sclerosis complex

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

Leucine induced dephosphorylation of Sestrin2 promotes mTORC1 activation

Authors

Scot R. Kimball, Bradley S. Gordon, Jenna E. Moyer, Michael D. Dennis, Leonard S. Jefferson,