Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10816137 | Cellular Signalling | 2013 | 17 Pages |
Abstract
A novel molecular organizational G-protein-coupled receptor(GPCR)-signaling platform potentiates neuraminidase-1(Neu1) and matrix metalloproteinase-9 (MMP-9) cross talk on the cell surface that is essential for the activation of receptor tyrosine kinases (RTKs).106
Keywords
Neu1MMPRag2Smad2PDGFIC50TLRFGFNGFRTKsStat1AktToll-like receptorCommon cytokine receptor γ chainPancreatic cancerepidermal growth factorVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)platelet-derived growth factornerve growth factorfibroblast growth factormatrix metalloproteinaseMatrix metalloproteinase-9receptor tyrosine kinases
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Authors
Alanna M. Gilmour, Samar Abdulkhalek, Timothy S.W. Cheng, Farah Alghamdi, Preethi Jayanth, Leah K. O'Shea, Olivia Geen, Luis A. Arvizu, Myron R. Szewczuk,