| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10816195 | Cellular Signalling | 2013 | 12 Pages |
Abstract
⺠p130Cas is a ubiquitously expressed adaptor protein. ⺠p130Cas is phosphorylated in response to integrin, RTK and GPCR signalling. ⺠p130Cas-mediated recruitment and activation of GEFs is critical for cell motility. ⺠Expression of p130Cas is essential for the development of the cardiovascular system. ⺠Aberrant p130Cas signalling contributes to the development of several human cancers.
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Authors
Angela Barrett, Caroline Pellet-Many, Ian C. Zachary, Ian M. Evans, Paul Frankel,