Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10816199 | Cellular Signalling | 2013 | 35 Pages |
Abstract
⺠Human osteoclasts express BMP receptors (BMPR-IA, BMPR-IB, ALK1, and BMPR-II). ⺠BMP-9 increases bone resorption, and reduces osteoclast apoptosis. ⺠BMP-9 induces phosphorylation of Smad-1/5/8 and ERK 1/2 proteins in osteoclasts.
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Authors
David Fong, Martine Bisson, Gino Laberge, Stephen McManus, Guillaume Grenier, Nathalie Faucheux, Sophie Roux,