Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10816215 | Cellular Signalling | 2013 | 15 Pages |
Abstract
⺠Compound C is an inhibitor of AMPK. ⺠Compound C inhibits cell proliferation by inducing Go/G1 cell cycle arrest. ⺠Compound C inhibits the phosphorylation of PDGFRβ but not EGFR and IGF1R. ⺠Compound C inhibits the in vitro tyrosine kinase activity of PDGFRβ. ⺠The inhibitory effect of Compound C on PDGFRβ is independent of AMPK.
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Authors
Hyun Jin Kwon, Go-Eun Kim, Yun Taek Lee, Meong-Sook Jeong, Insug Kang, Dongki Yang, Eui-Ju Yeo,