Article ID Journal Published Year Pages File Type
10816217 Cellular Signalling 2013 9 Pages PDF
Abstract
► C5L2 and C5aR form homo- and heterodimers in transfected HEK 293 cells. ► ASP and C5a stimulate C5L2/C5aR colocalization and internalization in adipocytes. ► There is little C5a-dependent colocalization in macrophages. ► C5L2-C5aR dimerization may explain the differential adipocyte ASP vs C5a response.
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