Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10816217 | Cellular Signalling | 2013 | 9 Pages |
Abstract
⺠C5L2 and C5aR form homo- and heterodimers in transfected HEK 293 cells. ⺠ASP and C5a stimulate C5L2/C5aR colocalization and internalization in adipocytes. ⺠There is little C5a-dependent colocalization in macrophages. ⺠C5L2-C5aR dimerization may explain the differential adipocyte ASP vs C5a response.
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Authors
Pegah Poursharifi, Marc Lapointe, Darlaine Pétrin, Dominic Devost, Danny Gauvreau, Terence E. Hébert, Katherine Cianflone,