Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10816218 | Cellular Signalling | 2013 | 12 Pages |
Abstract
⺠Src enhances constitutive and ligand-induced Usp8 tyrosine phosphorylation. ⺠TGFα-induced EGFR endosomal recycling leads to lower Usp8 tyrosine phosphorylation. ⺠The Usp8 MIT-domain is required for EGF-induced Usp8 1-504 tyrosine phosphorylation. ⺠The Usp8 Y679F mutation does not abolish phosphoserine-dependent 14-3-3 binding. ⺠Usp8 is a target for the post-translational serine and tyrosine phosphorylation.
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Authors
Inez M.J. Meijer, JoAnn Kerperien, Ana M. Sotoca, Everardus J.J. van Zoelen, Jeroen E.M. van Leeuwen,