Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10816224 | Cellular Signalling | 2013 | 8 Pages |
Abstract
⺠Ahsg (fetuin-A) inhibits the metabolic arm of insulin action involving Akt. ⺠Ahsg inhibits trafficking of the insulin-sensitive glucose transporter GLUT4. ⺠Shows that Ahsg functions independently of the 120-kD insulin receptor α-subunit ⺠Define the target of Ahsg action as the external 194 residue segment of the Ã-subunit ⺠Supports previous mouse knockout studies on insulin sensitivity and resistance
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Anton Scott Goustin, Nada Derar, Abdul B. Abou-Samra,