| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10816225 | Cellular Signalling | 2013 | 10 Pages |
Abstract
⺠An IFNα protein corona forms spontaneously around micro- or nanoparticles. ⺠Particle-bound IFNα induces JAK-STAT signaling for anti-viral defense. ⺠IFNα-coated spheres allow a prolonged release of IFNα and alter STAT1 signaling. ⺠Full JAK-STAT dependent gene expression requires continuous presence of IFNα. ⺠Novel tools to analyze JAK-STAT signaling.
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Authors
Sibyll Pollok, Torsten Ginter, Katharina Günzel, Jana Pieper, Andreas Henke, Roland H. Stauber, Werner Reichardt, Oliver H. Krämer,