| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10816307 | Cellular Signalling | 2012 | 12 Pages |
Abstract
⺠Pseudokinases are evolutionary counterparts of protein kinases. ⺠Pseudokinases can function as scaffold proteins, allosteric activators and/or as active kinases. ⺠Pseudokinases are involved in cellular signaling pathways of malignant cells.
Keywords
PRDpKaCCAAT/enhancer-binding protein-αFOXO3aAMLCCK4TFF1GSK3KSR1TGF-βERαLIMTRRAPMT1-MMPPJSTrefoil factor 1Tyk2Jnk1PP2AmTORJanus tyrosine kinaseAMPKphosphatidylinositol-3-OH kinaseATF4EGFRLKB1PI3KTNFαEGFIL-9C/EBPαTRBPIKKMAPKSTATsadenosine-5′-triphosphateATPMAGUKloss of heterozygosityDrug targetsILKInterleukin-9transforming growth factor-βtumour necrosis factor αtyrosine kinase 2forkhead box O3aCancerPeutz–Jeghers syndromeepidermal growth factormembrane associated guanylate kinasePhosphorylationAcute lymphoblastic leukaemiaAcute myeloid leukaemiaLOHsignal transducers and activators of transcriptionmembrane type-1 matrix metalloproteinasemammalian target of rapamycinALLHistone acetyltransferaseprotein phosphatase 2Aprotein kinase Amitogen-activated protein kinaseJAKCASKHATintegrin-linked kinaseliver kinase B1Kinasesglycogen synthase kinase 3Oestrogen receptor α
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Hua Zhang, Andrew Photiou, Arnhild Grothey, Justin Stebbing, Georgios Giamas,