| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10816315 | Cellular Signalling | 2012 | 8 Pages |
Abstract
⺠TNFα stimulates ceramide kinase in neuronal cells. ⺠Ceramide-1-phosphate directly activates a neuronal NADPH oxidase activity. ⺠Ceramide kinase activity is necessary for TNFα-stimulated eicosanoid biosynthesis in neuronal cells.
Keywords
DPIN-acetyl-l-cysteineDAPIcPLA2dichlorofluoresceinPICSMaseNACIDMEicosanoidDcfASMaseFITCNBDFBSDOTAPCOXMK-886C1PCERKTNFαPBS1,2-dioleoyl-sn-glycero-3-phosphoethanolamineBSAH2DCFDANOxROSbovine serum albumincyclooxygenaseacid sphingomyelinasesphingomyelinaseArachidonic acidinflammationIndomethacinNADPH oxidaseLOXOxidative stresstumor necrosis factor alphadiphenylene iodoniumCeramide kinaseCeramide-1-phosphatefetal bovine serumPhosphate buffered salinecytosolic phospholipase A2FluoresceinLipooxygenaseNeuronDOPEprotease inhibitor cocktailReactive oxygen species
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Authors
Brian M. Barth, Sally J. Gustafson, Jody L. Hankins, James M. Kaiser, Jeremy K. Haakenson, Mark Kester, Thomas B. Kuhn,