| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10816324 | Cellular Signalling | 2012 | 10 Pages |
Abstract
⺠LPA increases TGFBIp expression in human corneal fibroblasts. ⺠LPA induces TGFBIp expression by stimulating secretion of TGF-β1. ⺠Activation of JNK is involved in LPA-induced secretion of TGF-β1. ⺠Smad2/3 is involved in the LPA-induced TGFBIp expression. ⺠LPA-mediated activation of TGFBIp depends on LPA1 and autocrine secretion of TGF-β. ⺠LPA signaling may be used for the prevention of treatment for corneal diseases.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Eun Su Jeon, Jae Ho Kim, Hyunmi Ryu, Eung Kweon Kim,