Article ID Journal Published Year Pages File Type
10816365 Cellular Signalling 2012 11 Pages PDF
Abstract
► Human apelin receptor APJ forms a heterodimer with kappa opioid receptor. ► The heterodimer leads to increased ERK phosphorylation and SRE activity. ► The heterodimer leads to decreased cAMP and CRE activity. ► The heterodimer showed a significantly increase in cell proliferation.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Heterodimerization of human apelin and kappa opioid receptors: Roles in signal transduction
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