Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10816368 | Cellular Signalling | 2012 | 11 Pages |
Abstract
⺠BMP2 signals the ALK3-dependent loss of epithelial character in epicardial cells. ⺠BMP2-stimulated invasion is dependent on TGFβR3 interaction with GIPC. ⺠Invasion also requires activation of ALK2, ALK3, ALK5, and Smad4.
Keywords
CDC42Type III TGFβ receptorGIPCSmurf1TGFβR1TGFβR2RhoATGFβGFPPar6ALKEpicardiumTransforming Growth Factor BetaEpithelial-mesenchymal transformationDifferentiationInvasionEMTCoronary vesselsRas homolog gene family member ABMPgreen fluorescent proteinbone morphogenic proteinBone morphogenetic proteincell division control protein 42 homolog
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Cynthia R. Hill, Nora S. Sanchez, Joseph D. Love, Julian A. Arrieta, Charles C. Hong, Christopher B. Brown, Anita F. Austin, Joey V. Barnett,