Article ID Journal Published Year Pages File Type
10816374 Cellular Signalling 2012 6 Pages PDF
Abstract
► BCL11B tumor suppressor inhibits HMD2 expression in a p53-dependent manner. ► BCL11B associates with the HMD2 P2 promoter. ► BCL11B attenuates the p53-dependent HDM2 promoter activation after γ-irradiation. ► BCL11B may contribute to the regulation of p53-HDM2 feedback loop.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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BCL11B tumor suppressor inhibits HDM2 expression in a p53-dependent manner
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