Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10816376 | Cellular Signalling | 2012 | 11 Pages |
Abstract
⺠The 5-HT7a receptor interacts with RhoBTB3. ⺠The third intracellular loop of the 5-HT7a receptor is more critical for interaction with RhoBTB3 than the C-terminal tail. ⺠RhoBTB3 does not recruit Cul3/Roc1 to the 5-HT7a receptor nor does it mediate ubiquitination of the 5-HT7a receptor. ⺠RhoBTB3 inhibits proteasomal degradation of the 5-HT7a receptor.
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Authors
Anne Matthys, Kathleen Van Craenenbroeck, Béatrice Lintermans, Guy Haegeman, Peter Vanhoenacker,